Is Progesterone to Blame for Your Postpartum Anxiety?
- Jan 16, 2025
- 2 min read
Updated: Jun 2
Postpartum anxiety is more than just feeling worried every day. It involves persistent worry, restlessness, and intense fear that can disrupt daily life. It’s a serious condition that affects many new moms and it's often overlooked in discussions about postpartum health. Factors like sleep deprivation and the overwhelming responsibility of caring for a newborn can increase anxiety levels. While postpartum depression gets a lot of attention, postpartum anxiety can be just as challenging. In this blog post, I will explore the connection between hormonal changes, particularly progesterone, and anxiety during the postpartum period, as this is something I have personally struggled with.
The Role of Progesterone
Gaining insight into the hormonal shifts after childbirth can help to understand the roots of postpartum anxiety. During pregnancy, progesterone helps prepare the body for the growing baby and supports the pregnancy. After delivery, however, progesterone levels drop sharply. This sudden change can have significant emotional and physical effects, contributing to the anxiety many new moms may already feel. Fluctuations in hormones like progesterone can impact neurotransmitters in the brain such as serotonin and GABA, which are essential for maintaining mood stability. This feeling is not the same for everyone. Some may experience mild anxiety, while others may feel overwhelmed by these feelings.
One reason this shift can feel so intense is that progesterone doesn’t just affect the reproductive system—it also influences the nervous system. Progesterone is connected to a calming brain chemical called allopregnanolone, which supports GABA activity (often described as the brain’s “brake pedal”). When progesterone drops postpartum, allopregnanolone can drop too, and some women may feel more on edge, more reactive, or less able to “settle” after stress. At the same time, fluctuations in hormones like progesterone can impact neurotransmitters such as serotonin and GABA, which are essential for maintaining mood stability.

It took me over three years to understand that this was a key reason for my struggles with postpartum anxiety. After experiencing anxiety and tension for years, I made an appointment with a naturopathic doctor who conducted various lab tests. She discovered that while my progesterone levels appeared slightly below average to my OBGYN, they were not within optimal ranges. By making simple lifestyle changes and taking supplements, I was able to heal.
I hope my blog post helps you realize that postpartum anxiety is treatable, whether through natural methods or with professional assistance. Addressing the root cause can lead to more lasting healing and symptom management. Remember, you are not alone, and support is always available.
*If postpartum anxiety becomes too overwhelming, do not hesitate to reach out for assistance. Professionals, including therapists who specialize in postpartum issues, can offer personalized strategies for coping. Online-Therapy.com is a great resource if you're not quite ready for in-person therapy. In some cases, hormone therapy may be necessary but there are many different natural options, such as supplements or bioidentical treatment options that you can try out first. Open and honest conversations with your healthcare providers about symptoms are essential to managing anxiety effectively.




